
Kidney health is often overlooked until the first serious symptoms appear. Over 800 million people worldwide suffer from chronic kidney disease, which can remain silent until a urine test shows albumin, a protein indicating kidney damage.
One of the main factors accelerating kidney deterioration is the excessive or improper use of certain medications.
Below are some of the most commonly used medications that, if not properly managed, can impact kidney function:
1. Omeprazole and other proton pump inhibitors (PPIs)
Omeprazole is commonly prescribed for reflux, heartburn, and ulcers. However, long-term use without medical guidance can lead to acute kidney injury or chronic kidney disease. Always consult a specialist and avoid self-medicating.
Alternative: H2 blockers, such as famotidine or ranitidine, are generally safer for individuals without pre-existing kidney issues.

2. Ibuprofen and other nonsteroidal anti-inflammatory drugs (NSAIDs)
This popular painkiller can reduce blood flow to the kidneys, causing acute injury, particularly in older adults or those with kidney problems. Risk increases with prolonged use or high doses.
Recommendation: Do not take for more than 10 consecutive days without medical supervision.
3. Pain relievers such as aspirin, naproxen, and diclofenac
Overuse of NSAIDs can lead to fluid retention, elevated blood pressure, and chronic kidney disease. Watch for symptoms like bloating, fatigue, nausea, and decreased urination.
4. Aminoglycoside antibiotics
Drugs like gentamicin or amikacin, while effective for serious infections, can be toxic to the nephrons that filter blood and produce urine. Strict medical supervision is essential.
5. Lithium for bipolar disorder
Long-term lithium use may result in kidney failure or nephrogenic diabetes insipidus. Patients should be closely monitored by both nephrologists and psychiatrists.
6. Diuretics
Though helpful for treating hypertension and fluid retention, diuretics increase kidney workload and can cause dehydration, electrolyte imbalances, and eventual kidney failure.
7. Blood pressure medications
Certain renin-angiotensin system (RAS) inhibitors may impact kidney function over time. Do not stop these medications without medical advice, as they are essential for controlling hypertension.

Tips to protect your kidneys:
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Monitor your blood pressure regularly.
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Maintain a healthy weight.
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Control blood sugar levels if diabetic.
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Have routine urine tests to detect proteinuria.
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Avoid self-medication, even with over-the-counter drugs.
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Eliminate harmful habits like smoking and excessive alcohol use.
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Keep cardiovascular factors, such as cholesterol and triglycerides, under control.